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DHA Research & Development
U.S. Army Medical Research & Development Command
RESOURCES

Amendment Submission Instructions

ACURO must review and approve significant changes/major modifications to animal work subject to ACURO oversight BEFORE the modifications can be implemented The ACURO Protocol Change Policy defines significant changes/major modification that require submission to ACURO. Minor changes/minor modifications, as defined in the ACURO Protocol Change Policy, do not require ACURO review and approval.

Minor changes/minor modifications
(extramural and intramural):

  • Submission to ACURO is not required

Significant changes/major modifications
(extramural and intramural):

  • Submit the documents listed below for processing to usarmy.detrick.medcom-usamrmc.other.acuro@health.mil
    • IACUC amendment approval
    • For changes in protocol PI, a signed ACURO PI Assurances MUST be provided.
    • IACUC approved amendment
  • When submitting a revised protocol as an amendment, the protocol MUST be highlighted to show where changes can be found, specifically what parts of the protocol were amended. Alternatively, provide a detailed description of the changes made along with a statement that no other changes were made to the protocol besides those indicated.


Questions regarding ACURO protocol review processes should be directed to ACURO at
Phone: 301-619-6694
Email: usarmy.detrick.medcom-usamrmc.other.acuro@health.mil

Last Modified Date: 06-Jan-2026